Aparna Sundaram, MD

Associate Professor of Medicine
Division of Pulmonary and Critical Care
[email protected]
+1 415 514-8363

[email protected]

Aparna is a California native. She completed her undergraduate, medical school, internship, and residency in Chicago, before returning to California for fellowship in Pulmonary and Critical Care Medicine and postdoctoral research training at UCSF. She is a firm believer in the importance of longitudinal mentorship, and is always up for a hot cup of tea with friends.

Publications: 

Integrin a2ß1 regulates collagen I tethering to modulate hyperresponsiveness in reactive airway disease models.

The Journal of clinical investigation

Liu S, Ngo U, Tang XZ, Ren X, Qiu W, Huang X, DeGrado W, Allen CD, Jo H, Sheppard D, Sundaram AB

Dual antagonists of a5ß1/ avß1 integrin for airway hyperresponsiveness.

Bioorganic & medicinal chemistry letters

Sundaram A, Chen C, Isik Reed N, Liu S, Ki Yeon S, McIntosh J, Tang YZ, Yang H, Adler M, Beresis R, Seiple IB, Sheppard D, DeGrado WF, Jo H

G protein-regulated endocytic trafficking of adenylyl cyclase type 9.

eLife

Lazar AM, Irannejad R, Baldwin TA, Sundaram AB, Gutkind JS, Inoue A, Dessauer CW, Von Zastrow M

A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion.

The Journal of biological chemistry

Del Cid JS, Reed NI, Molnar K, Liu S, Dang B, Jensen SA, DeGrado W, Handford PA, Sheppard D, Sundaram AB

IL-17A Recruits Rab35 to IL-17R to Mediate PKCa-Dependent Stress Fiber Formation and Airway Smooth Muscle Contractility.

Journal of immunology (Baltimore, Md. : 1950)

Bulek K, Chen X, Parron V, Sundaram A, Herjan T, Ouyang S, Liu C, Majors A, Zepp J, Gao J, Dongre A, Bodaszewska-Lubas M, Echard A, Aronica M, Carman J, Garantziotis S, Sheppard D, Li X

Targeting integrin a5ß1 ameliorates severe airway hyperresponsiveness in experimental asthma.

The Journal of clinical investigation

Sundaram A, Chen C, Khalifeh-Soltani A, Atakilit A, Ren X, Qiu W, Jo H, DeGrado W, Huang X, Sheppard D

G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands.

Molecular pharmacology

Tsvetanova NG, Trester-Zedlitz M, Newton BW, Riordan DP, Sundaram AB, Johnson JR, Krogan NJ, von Zastrow M

IQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction.

The Journal of clinical investigation

Bhattacharya M, Sundaram A, Kudo M, Farmer J, Ganesan P, Khalifeh-Soltani A, Arjomandi M, Atabai K, Huang X, Sheppard D

The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.

The Journal of clinical investigation

Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A

The avß6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

The Journal of clinical investigation

Sugimoto K, Kudo M, Sundaram A, Ren X, Huang K, Bernstein X, Wang Y, Raymond WW, Erle DJ, Abrink M, Caughey GH, Huang X, Sheppard D